时雨副主任医师 |
时雨，男，1981年3月出生，胸心外科学博士。2009年毕业于复旦大学附属中山医院胸心外科学专业，硕博连读。毕业后于复旦大学附属中山医院胸外科工作至今，2015年晋升为副主任医师。对胸外科各种常见疾病有着丰富的诊疗经验，擅长肺部及纵隔肿瘤的微创治疗。
近年来作为负责人承担教育部高等学校博士学科点专项科研基金（新教师类）（TRPC6
通道对食管鳞癌放疗增敏作用机理及临床应用的基础研究）、上海市卫计委科研课题面上项目（食管鳞癌中miR-135a-5p通过TRPC6对放疗效果的调控作用研究）各一项。另作为主要参与人参加国家级课题3项、省部级课题1项，其它课题2项。发表论文获得国家发明专利1项（SFTA3基因在肺鳞癌和腺癌病理诊断鉴别中的应用，第五发明人）。作为导师组成员指导已毕业硕士生3人，担任World
Journal of Gastroenterology、Oncology Reports等多本SCI期刊审稿人。
近年来以第一作者或通讯作者发表SCI论著9篇，其中博士论文发表在国际著名消化病杂志GUT(2015
IF：14.921)。
代表性论文：
[1] Sun F, Zhan C, Shi M, et al. Is routine dissection of the
station 9 lymph nodes really necessary for primary lung cancer?
INT J SURG 2016; 34: 53-7.
[2] Zhan C, Yan L, Wang L, et al. Isoform switch of pyruvate
kinase M1 indeed occurs but not to pyruvate kinase M2 in human
tumorigenesis. PLOS ONE 2015; 10(3): e118663.
[3] Zhan C, Yan L, Wang L, et al. Identification of
immunohistochemical markers for distinguishing lung
adenocarcinoma from squamous cell carcinoma. J Thorac Dis 2015;
7(8): 1398-405.
[4] Zhan C, Yan L, Wang L, et al. Landscape of expression
profiles in esophageal carcinoma by The Cancer Genome Atlas
data. DIS ESOPHAGUS 2015.
[5] Zhan C, Zhang Y, Ma J, et al. Identification of reference
genes for qRT-PCR in human lung squamous-cell carcinoma by RNA-Seq.
Acta Biochim Biophys Sin (Shanghai) 2014; 46(4): 330-7.
[6] Zhan C, Yan L, Wang L, et al. Identification of reference
miRNAs in human tumors by TCGA miRNA-seq data. Biochem Biophys
Res Commun 2014; 453(3): 375-8.
[7] Wang L, Zhan C, Zhang Y, et al. Quantifying the expression
of tumor marker genes in lung squamous cell cancer with RNA
sequencing. J Thorac Dis 2014; 6(10): 1380-7.
[8] Zhan C, Shi Y, Lu C, Wang Q. Pyruvate kinase M2 is highly
correlated with the differentiation and the prognosis of
esophageal squamous cell cancer. DIS ESOPHAGUS 2013; 26(7):
746-53.
[9] Shi Y, Ding X, He ZH, Zhou KC, Wang Q, Wang YZ. Critical
role of TRPC6 channels in G2 phase transition and the
development of human oesophageal cancer. GUT 2009; 58(11):
1443-50.
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